Choline has an antioxidant-like impact on the body by decreasing the oxidative stress from homocysteine. It has been clearly demonstrated that homocysteine has negative impacts on health. It is known to promote the production of free radicals, resulting in oxidative stress. Choline, a vitamin-like essential nutrient, has been shown to directly reduce homocysteine in the body. Choline deficiency can cause muscle damage and abnormal fat accumulation in the liver.
If left unchecked, free radicals, or Reactive Oxygen Species (ROS) can cause extensive damage to the body’s cells and tissues through the process of oxidative stress. Superoxide is a by-product of normal oxygen metabolism and a harmful ROS. If not regulated, superoxide can cause cellular damage. The inadequate removal of ROS, especially superoxide anion, leads to oxidative stress.
Superoxide Dimutase (SOD), on the other hand, is an enzyme that plays an important role as an antioxidant that helps neutralize superoxide radicals. Copper, zinc, manganese and selenium play a number of roles on their own in protecting the body from the potential negative effects of free radicals. These elements can be even more effective when they are incorporated into their associated SOD compounds.
As stated in this newsletter, the trace minerals Copper, Zinc, Manganese, and Selenium all have roles as antioxidants. As such, they help the body fight against the health dangers that can come from free radical damage. In addition, Choline helps fight against the oxidative stress imposed by homocysteine, and therefore plays a related antioxidant role.
Look for the next newsletter from Albion Human Nutrition.